Recombinant monoclonal antibody Inolimomab is a mouse monoclonal antibody that specifically binds to human IL-2Rα and can be potentially used in the treatment of graft versus host disease.
Figure 1 Kaplan–Meier OS (left) and TRM (right) curves of corticosteroid refractory aGVHD patients treated with Inolimomab from the time of HSCT.
At 3 years: OS=54.5% (95% CI=36.3–69.6%) and TRM=29.7% (95% CI=16.6–49.6%).
Girerd, S., Renaud, M., Guilhot, J., Giraud, C., Larchee, R., Jollet, I., & Guilhot, F. (2013). Long-term follow-up of corticosteroid refractory acute GVHD treated with an Inolimomab-based algorithm: a single center experience. Bone marrow transplantation, 48(9), 1243.
Figure 2 Kaplan–Meier OS curves of the two significant prognostic factors: response to Inolimomab (left, P<0.01) and age of patient (right, P<0.05).
Girerd, S., Renaud, M., Guilhot, J., Giraud, C., Larchee, R., Jollet, I., & Guilhot, F. (2013). Long-term follow-up of corticosteroid refractory acute GVHD treated with an Inolimomab-based algorithm: a single center experience. Bone marrow transplantation, 48(9), 1243.
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• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
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CAT | Product Name | Application | Type |
---|---|---|---|
IAB-B073(A) | Recombinant Anti-human IL2RA Intrabody [(D-Arg)9] | IF, ELISA, FuncS | scFv-(D-Arg)9 |
IAB-B073(G) | Recombinant Anti-human IL2RA Intrabody [+36 GFP] | IF, FC, WB, FuncS | scFv-(+36GFP) |
IAB-B073(T) | Recombinant Anti-human IL2RA Intrabody [Tat] | WB, CO-IP, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-023 | Anti-Human CD25 Recombinant Antibody (Daclizumab) | ELISA, Neut, IF, IP, FC, FuncS | IgG1 - kappa |
TAB-646LC-F(E) | Anti-human IL2RA Fab Fragment (48M54S) | ELISA, FC | Humanized antibody |
TAB-647LC-F(E) | Anti-human IL2RA Fab Fragment (48M51L) | ELISA, FC | Humanized antibody |
TAB-648LC-F(E) | Anti-human IL2RA Fab Fragment (48V54S) | ELISA, FC | Humanized antibody |
TAB-649LC-F(E) | Anti-human IL2RA Fab Fragment (Dmab) | FC | Humanized antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-004 | Anti-Human CD25 Recombinant Antibody (Basiliximab) | IF, IP, Neut, FuncS, ELISA, FC, ICC | IgG1 - kappa |
PABX-030 | Recombinant Human Anti-CD25 Antibody (SDZCHII621) | Neut, FuncS | IgG |
PABX-030-F (E) | Recombinant Mouse Anti-CD25 Antibody Fab Fragment (SDZCHII621) | Neut, FuncS | Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-155 | Anti-Human CD25 Recombinant Antibody (Inolimomab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 - kappa |
TAB-641LC | Anti-human IL2RA Recombinant Antibody (Inolimomab) (TAB-641LC) | ELISA | |
TAB-641LC-F(E) | Anti-human IL2RA Fab Fragment (Inolimomab) | ELISA | |
PABX-029-S (P) | Recombinant Human Anti-CD25 Antibody scFv Fragment (Daclizumab) | WB, ELISA, FuncS | scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
AGTO-L028E | anti-IL2RA immunotoxin RFT5 (IgG)-PE | Cytotoxicity assay, Functional assay | |
AGTO-L028D | anti-IL2RA immunotoxin RFT5 (IgG)-DT | Cytotoxicity assay, Functional assay | |
AGTO-L078E | IL2-PE immunotoxin | Cytotoxicity assay, Functional assay | |
AGTO-L078D | IL2-DT immunotoxin | Cytotoxicity assay, Functional assay | |
AGTO-L078R | IL2-RTA immunotoxin | Cytotoxicity assay, Functional assay |
CAT | Product Name | Application | Type |
---|---|---|---|
PFBZ-020 | Human Anti-IL2RA Recombinant Antibody (clone CHI621); Fab Fragment | Block | Chimeric (mouse/human) Fab |
PFBZ-082 | Human Anti-IL2RA Recombinant Antibody (clone SDZ CHI621); Fab Fragment | Block | Chimeric (mouse/human) Fab |
HPAB-0060-FY-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (HPAB-0060-FY-F(E)) | ELISA | Humanized Fab |
HPAB-2113-FY-F(E) | Mouse Anti-IL2RA Recombinant Antibody (clone MAK179); Fab Fragment | Inhib | Mouse Fab |
HPAB-1536WJ-F(E) | Rat Anti-IL2RA Recombinant Antibody; Fab Fragment (clone YTH 906.9.21) | ELISA, WB | Rat Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
PSBZ-020 | Mouse Anti-IL2RA Recombinant Antibody (clone CHI621); scFv Fragment | Block | Mouse scFv |
HPAB-0060-FY-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0060-FY-S(P)) | ELISA | Humanized scFv |
HPAB-M0454-YC-S(P) | Mouse Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-M0454-YC-S(P)) | ELISA | Mouse scFv |
HPAB-0559-WJ-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (HPAB-0559-WJ-S(P)) | ELISA, FC | Human scFv |
HPAB-1536WJ-S(P) | Rat Anti-IL2RA Recombinant Antibody; scFv Fragment (clone YTH 906.9.21) | ELISA, WB | Rat scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-642LC-S(P) | Human Anti-IL2RA Recombinant Antibody; scFv Fragment (TAB-642LC-S(P)) | ELISA, FC | Human scFv |
TAB-642LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-642LC-F(E)) | ELISA, FC | Human Fab |
TAB-643LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-643LC-F(E)) | ELISA, FC | Human Fab |
TAB-644LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-644LC-F(E)) | ELISA, FC | Human Fab |
TAB-645LC-F(E) | Human Anti-IL2RA Recombinant Antibody; Fab Fragment (TAB-645LC-F(E)) | ELISA, FC | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1344CQ | Mouse Anti-IL2RA Recombinant Antibody (clone B-B10) | FC, Neut, WB, IF | Mouse IgG1, κ |
NEUT-1345CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL017) | Neut, WB, IHC | Mouse IgG1 |
NEUT-1346CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL242) | ELISA, FC, Neut | Mouse IgG1, κ |
NEUT-1348CQ | Mouse Anti-IL2RA Recombinant Antibody (clone CBL726) | WB, IHC, ICC, Neut | Mouse IgG1 |
NEUT-1349CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 1X27) | IHC, Neut, WB | Mouse IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-1350CQ | Mouse Anti-IL2RA Recombinant Antibody (clone 2R12) | Block, FC, ICC, IF, IHC, IP, WB | Mouse IgG1 |
NEUT-1356CQ | Rat Anti-Il2ra Recombinant Antibody (VMC199) | FC, IP, IHC, Block, Depletion | Rat IgG1, λ |
NEUT-1357CQ | Rat Anti-Il2ra Recombinant Antibody (clone 3C7) | FC, IP, Inhib | Rat IgG2b, κ |
NEUT-1358CQ | Rat Anti-Il2ra Recombinant Antibody (clone mAb0817) | Block, Depletion | Rat IgG1 |
NEUT-1359CQ | Rat Anti-Il2ra Recombinant Antibody (clone mAb0845) | Block, FC, IHC-Fr, IP | Rat IgG1 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1808 | Rabbit Anti-IL2RA Recombinant Antibody (clone DS1808AB) | IHC, ICC, IP | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
AFC-TAB-004 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Basiliximab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
AFC-TAB-023 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Daclizumab), ADCC Enhanced | ELISA, Neut, IF, IP, FC, FuncS | ADCC enhanced antibody |
AFC-TAB-155 | Afuco™ Anti-IL2RA ADCC Recombinant Antibody (Inolimomab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0559-WJ | Human Anti-IL2RA Recombinant Antibody (HPAB-0559-WJ) | ELISA, Inhib, FuncS, FC | Human IgG |
HPAB-0560-WJ | Human Anti-IL2RA Recombinant Antibody (HPAB-0560-WJ) | ELISA, Inhib, FuncS, FC | Human IgG |
HPAB-0561-WJ | Human Anti-IL2RA Recombinant Antibody (HPAB-0561-WJ) | ELISA, Inhib, FuncS, FC | Human IgG |
HPAB-2113-FY | Mouse Anti-IL2RA Recombinant Antibody (clone MAK179) | Inhib | Mouse IgG |
VS3-WK1240 | Mouse Anti-IL2RA Recombinant Antibody (VS3-WK1240) | WB | Mouse IgG1 |
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For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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