Afuco™ Anti-CD40 ADCC Recombinant Antibody (Bleselumab), ADCC Enhanced (CAT#: AFC-TAB-006ML)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to CD40. Bleselumab is a human monoclonal antibody that can be potentially used in the treatment of Lymphoma, B cell.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Lymph node
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg
Figure 2 Tonsil
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg
(Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg
Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Human
- Type
- ADCC enhanced antibody
- Specificity
- Human CD40
- Species Reactivity
- Human
- Clone
- Bleselumab
- Applications
- ELISA, IHC, FC, IP, IF, Inhib
- Conjugate
- Unconjugated
- Generic Name
- Bleselumab
- Related Disease
- Lymphoma, B cell
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Tumor necrosis factor receptor superfamily member 5; TNFRSF5; p50
- Gene ID
- 958
- UniProt ID
- P25942
Related Resources
Please refer to Bleselumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Bleselumab.
Asthma
Systemic Lupus Erythematosus
Primary Immunodeficiency
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Bleselumab"
Anti-Human CD40 Recombinant Antibody (Bleselumab)Recombinant monoclonal antibody to CD40. Bleselumab is a human monoclonal antibody that can be potentially used in the treatment of Lymphoma, B cell.
See other products for "CD40"
Select a product category from the dropdown menu below to view related products.
Please select product type
Chimeric Antibody
Immunotoxin
Humanized Antibody
Mouse Antibody
Human Antibody
Blocking Antibody
Neutralizing Antibody
Rabbit Monoclonal Antibody
Agonistic Antibody
Recombinant Antibody
Neuroscience Antibody
Fab Fragment Antibody
ADCC Enhanced Antibody
Single-domain Antibody
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-262 | Anti-Human CD40 Recombinant Antibody (Teneliximab) | IP, IF, FuncS, FC, Neut, ELISA, ICC | IgG1 |
| TAB-188LC-S(P) | Anti-Human CD40 Recombinant Antibody scFv Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
| TAB-188LC-F(E) | Anti-Human CD40 Recombinant Antibody Fab Fragment (chi220) | SPR, ELISA | Chimeric antibody (mouse/human) |
| TAB-202LC-F(E) | Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-202LC-F(E)) | FC, ELISA | Chimeric antibody (mouse/rhesus) |
| TAB-203LC-F(E) | Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-203LC-F(E)) | FC, ELISA | Chimeric antibody (mouse/rhesus) |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for AFC-TAB-006ML. Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
![Figure 1 Anti-Human CD19 Recombinant Antibody Fab Fragment [TAB-1611CL-F(E)] in SDS-PAGE](https://img.creativebiolabs.net/productimages/COA-TAB-1611CL-F(E)-1.png)
Application: Depletion, FuncS
Application: Neut, ELISA, FuncS
Application: WB, ELISA, FC, IHC, IF, IP
Application: Neut, FuncS, IHC, ELISA, FC, Inhib
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
