Human Anti-CD40 Recombinant Antibody (clone LOB7-6) (CAT#: FAMAB-1063CQ)
This product is a recombinant human antibody that recognizes CD40. The antibody was purified by affinity chromatography. It can be used in ELISA.
Specific Inquiry
WB
Figure 1 Epitope Mapping of Anti-hCD40 mAbs.
C-terminally His-tagged CD40 proteins consisting of 4, 3, or 2 CRD domains (4 = full-length; 3 = CRD1 deleted; 2 = CRD1 and CRD2 deleted) were analyzed by western blotting with the LOB7-6 mAb used for detection. A composite image from multiple blots with different antibodies is shown.
Yu, X., Chan, H. C., Orr, C. M., Dadas, O., Booth, S. G., Dahal, L. N., ... & Duriez, P. (2018). Complex interplay between epitope specificity and isotype dictates the biological activity of anti-human CD40 antibodies. Cancer cell, 33(4), 664-675.
FC
Figure 2 Cells transfected with full-length (WT) human CD40 in which N-terminal amino acids 23-37 had been deleted, were incubated with the indicated anti-hCD40 mAb.
Bound mAbs were detected with anti-human Fc-FITC. The percentage of cells in the boxed region, denoting positive staining, is shown for each plot. Results from one of two experiments shown.
Yu, X., Chan, H. C., Orr, C. M., Dadas, O., Booth, S. G., Dahal, L. N., ... & Duriez, P. (2018). Complex interplay between epitope specificity and isotype dictates the biological activity of anti-human CD40 antibodies. Cancer cell, 33(4), 664-675.
Specifications
- Host Species
- Human
- Type
- Human IgG1
- Species Reactivity
- Human
- Clone
- LOB7-6
- Applications
- WB, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been reported for use in Western Blot and Flow Cytometry.
Target
- Alternative Names
- CD40 Molecule; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily, Member 5
- Gene ID
- 958
- UniProt ID
- P25942
Related Resources
Asthma
Systemic Lupus Erythematosus
Primary Immunodeficiency
Allograft Rejection
Autoimmune Thyroid Disease
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Clone LOB7-6"
See other products for "CD40"
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-759 | Anti-CD40 Recombinant Antibody (Lucatumumab) | ELISA, FC, IP, FuncS, IF, Neut, IHC | IgG1 - kappa |
| TAB-195LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-195LC-S(P)) | ELISA | Human scFv |
| TAB-196LC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-196LC-S(P)) | ELISA | Human scFv |
| TAB-006ML | Anti-Human CD40 Recombinant Antibody (Bleselumab) | ELISA, IHC, FC, IP, IF, Inhib | IgG4, κ |
| TAB-470CQ | Anti-Human CD40 Recombinant Antibody (Selicrelumab) | ELISA, IHC, FC, IP, IF, FuncS | IgG2, κ |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G079E | Anti-CD40 immunotoxin G28-5 (scFv)-PE | Cytotoxicity assay, Function study |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-189LC | Anti-Human CD40 Recombinant Antibody (F4) | SPR, ELISA | Humanized antibody |
| TAB-190LC | Anti-Human CD40 Recombinant Antibody (L3.17) | SPR, ELISA | Humanized antibody |
| TAB-194LC | Human Anti-CD40 Recombinant Antibody (TAB-194LC) | ELISA | Humanized IgG1, κ |
| TAB-200LC | Human Anti-CD40 Recombinant Antibody (TAB-200LC) | ELISA | Human IgG1, κ |
| TAB-204LC | Human Anti-CD40 Recombinant Antibody (TAB-204LC) | SPR, ELISA | Human IgG |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-207LC | Mouse Anti-CD40 Recombinant Antibody (TAB-207LC) | ELISA | Mouse IgG, κ |
| TAB-208LC | Mouse Anti-CD40 Recombinant Antibody (TAB-208LC) | ELISA | Mouse IgG, κ |
| TAB-209LC | Mouse Anti-CD40 Recombinant Antibody (TAB-209LC) | ELISA | Mouse IgG, κ |
| TAB-208LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-208LC-S(P)) | ELISA | Mouse scFv |
| TAB-209LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-209LC-S(P)) | ELISA | Mouse scFv |
Chimeric Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-192LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-192LC-S(P)) | ELISA | Mouse scFv |
| TAB-193LC-S(P) | Mouse Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-193LC-S(P)) | ELISA | Mouse scFv |
| TAB-202LC-S(P) | Anti-CD40 Recombinant Antibody; scFv Fragment (TAB-202LC-S(P)) | FC, ELISA | scFv |
| TAB-192LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-192LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-193LC-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (TAB-193LC-F(E)) | ELISA | Chimeric (mouse/human) Fab |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1129MZ | Mouse Anti-CD40 Recombinant Antibody (clone 93206) | ELISA | Mouse IgG2b |
| HPAB-1110LY | Mouse Anti-CD40 Recombinant Antibody (clone CBL020) | ELISA | Mouse IgG |
| HPAB-1662LY | Mouse Anti-CD40 Recombinant Antibody (HPAB-1662LY) | ELISA, RIA, Antagonist | Mouse IgG |
| HPAB-1663LY | Mouse Anti-CD40 Recombinant Antibody (HPAB-1663LY) | ELISA, RIA | Mouse IgG |
| HPAB-1664LY | Mouse Anti-CD40 Recombinant Antibody (HPAB-1664LY) | ELISA, RIA | Mouse IgG |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-362CQ | Human Anti-CD40 Recombinant Antibody (clone 5D12) | Block, ELISA, FC, SPR, IP, IHC | Human IgG4, κ |
| NEUT-363CQ | Mouse Anti-CD40 Recombinant Antibody (clone 5C3) | FC, Block, Activ | Mouse IgG1, κ |
| NEUT-365CQ | Hamster Anti-CD40 Recombinant Antibody (clone HM40-3) | FC, Block, Costim, IHC | Hamster IgM |
| NEUT-366CQ | Rat Anti-CD40 Recombinant Antibody (clone MAB0819) | Block, Activ | Rat IgG2 |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-364CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL829) | WB, Neut | Mouse IgG2b, κ |
| NEUT-367CQ | Mouse Anti-CD40 Recombinant Antibody (clone CBL013) | WB, IHC, Neut | Mouse IgG2 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-4059 | Hi-Affi™ Rabbit Anti-CD40 Recombinant Antibody (clone SI126DS) | ELISA | Rabbit IgG |
Agonistic Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-105LC | Human Anti-CD40 Recombinant Antibody (MOB-105LC) | FC, FuncS | Human IgG1, κ |
| MOB-106LC | Human Anti-CD40 Recombinant Antibody (MOB-106LC) | FC, FuncS, ELISA | Human IgG2, κ |
| MOB-107LC | Human Anti-CD40 Recombinant Antibody (MOB-107LC) | FC, FuncS, ELISA | Human IgG2, κ |
Neuroscience Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-021CN | Human Anti-CD40 Recombinant Antibody (NS-021CN) | ELISA, IF, Block, FuncS | Human IgG |
| NS-021CN-F(E) | Human Anti-CD40 Recombinant Antibody; Fab Fragment (NS-021CN-F(E)) | ELISA | Human Fab |
| NS-021CN-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (NS-021CN-S(P)) | ELISA | Human scFv |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1110LY-S(P) | Mouse Anti-CD40 Recombinant Antibody (clone CBL020); scfv Fragment | ELISA | Mouse scfv |
| HPAB-M0030-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-M0030-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-M0031-YC-S(P) | Human Anti-CD40 Recombinant Antibody; scFv Fragment (HPAB-M0031-YC-S(P)) | ELISA, FuncS | Human scFv |
| HPAB-0710-FY-F(E) | Mouse Anti-CD40 Recombinant Antibody (clone AB009); scFv Fragment | ELISA | Mouse scFv |
| HPAB-1834-FY-F(E) | Human Anti-CD40 Recombinant Antibody (clone 21.4.1); scFv Fragment | Agonist, Activ | Human scFv |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1110LY-F(E) | Mouse Anti-CD40 Recombinant Antibody (clone CBL020); Fab Fragment | ELISA | Mouse Fab |
| HPAB-1662LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1662LY-F(E)) | ELISA, RIA | Mouse Fab |
| HPAB-1663LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1663LY-F(E)) | ELISA, RIA | Mouse Fab |
| HPAB-1664LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1664LY-F(E)) | ELISA, RIA | Mouse Fab |
| HPAB-1665LY-F(E) | Mouse Anti-CD40 Recombinant Antibody; Fab Fragment (HPAB-1665LY-F(E)) | ELISA, RIA | Mouse Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-152 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Dacetuzumab), ADCC Enhanced | IF, IP, Neut, FuncS, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-262 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Teneliximab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| AFC-TAB-759 | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Lucatumumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-470CQ | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Selicrelumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, FuncS | ADCC enhanced antibody |
| AFC-TAB-006ML | Afuco™ Anti-CD40 ADCC Recombinant Antibody (Bleselumab), ADCC Enhanced | ELISA, IHC, FC, IP, IF, Inhib | ADCC enhanced antibody |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1218WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (CD40-1) | ELISA | Llama VHH |
| HPAB-1219WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (CD40-2) | ELISA | Llama VHH |
| HPAB-1220WJ | Recombinant Llama Anti-CD40 Single Domain Antibody (CD40-3) | ELISA | Llama VHH |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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