Does this antibody detect Amyloid beta?

Yes, this recombinant mouse antibody specifically recognizes amyloid beta (APP). It is suitable for ELISA applications to detect this protein, which is a key component of amyloid plaques found in Alzheimer's disease.

What is the isotype of this antibody?

This is a Mouse IgG2a, kappa antibody. It reacts with Human APP and was purified by affinity chromatography. It is supplied in PBS without preservatives and should be stored at -20°C for long term stability.

Mouse Anti-APP Recombinant Antibody (TAB-0781CLV)

CAT#: TAB-0781CLV

This product is a recombinant mouse antibody that recognizes amyloid beta. The antibody was purified by affinity chromatography. This antibody is recommended in ELISA.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/if_selected.jpg

Subcellular Location Figure 2 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/60_E2_1_blue_red_green.jpg

Subcellular Location Figure 3 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/61_E2_1_blue_red_green.jpg

Normal Tissue Figure 4 Cerebral cortex

Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/157/2073_B_7_5.jpg

RNA Expression Figure 5 RNA cell line category: Low cell line specificity

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP

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Specifications

Immunogen
Amylospheroid 42

Host Species
Mouse

Type
Mouse IgG2a, κ

Specificity
Human

Species Reactivity
Human

Applications
ELISA

Related Disease
Alzheimer's disease

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
APP; Amyloid Beta; amyloid beta (A4) precursor protein

Gene ID
351

UniProt ID
P05067

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Breast cancer biomarkers at key points during disease progression

Detects Amyloid Beta

We used this antibody in ELISA to quantify amyloid beta levels. It recognized the target effectively and helped in our Alzheimer's disease research. The mouse IgG2a isotype was suitable for our secondary antibodies.

Consistent Quality

This recombinant antibody provided consistent results across multiple assays. We appreciate the high purity verified by SDS-PAGE. It is a reliable reagent for studying the precursor protein and its cleavage products.

Q&As

Does this antibody detect Amyloid beta?

A: Yes, this recombinant mouse antibody specifically recognizes amyloid beta (APP). It is suitable for ELISA applications to detect this protein, which is a key component of amyloid plaques found in Alzheimer's disease.
What is the isotype of this antibody?

A: This is a Mouse IgG2a, kappa antibody. It reacts with Human APP and was purified by affinity chromatography. It is supplied in PBS without preservatives and should be stored at -20°C for long term stability.

View the frequently asked questions answered by Creative Biolabs Support.

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Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-0781CLV.pdf

MSDS

MSDS - TAB-0781CLV.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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MOR-0220	Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone DS220AB)	ELISA, WB	Rabbit IgG

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MOR-0082-FY	Rabbit Anti-APP Recombinant Antibody (clone AFY0053)	ICC, IHC-P, WB	Rabbit IgG

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VS-0424-XY17	AbPlus™ Anti-APP Magnetic Beads (DE2B4)	IP, Protein Purification

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CAT	Product Name	Application	Type
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CAT	Product Name	Application	Type
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VS-0525-YC196	Recombinant Anti-APP (AA 1-5 x AA 13-28) Biparatopic Antibody, Tandem scFv	ELISA, FC, IF, IP, Neut, WB	Tandem scFv

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VS-0525-YC198	Recombinant Anti-APP (AA 13-28 x AA 33-40) Biparatopic Antibody, Tandem scFv (Solanezumab x Ponezumab)	ELISA, FC, IF, IP, Neut, WB	Tandem scFv

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