Mouse Anti-ERBB3 Recombinant Antibody (ZG-0313J) (CAT#: ZG-0313J)

Name: Mouse Anti-ERBB3 Recombinant Antibody (ZG-0313J)
SKU: ZG-0313J
Rating: 5 (1 reviews)

This product is a mouse antibody that recognizes ERBB3.

Custom Production

We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

We require custom production

Tested Data
Gene Expression
Datasheet
MSDS
COA

Figure 1 Mouse Anti-ERBB3 Recombinant Antibody (ZG-0313J) in WB

Figure 1 Mouse Anti-ERBB3 Recombinant Antibody (ZG-0313J) in WB

Western Blot analysis using ErbB-3 Monoclonal Antibody against truncated Trx-ErbB-3 recombinant protein (1) and MBP-ErbB-3 (aa1175-1275) recombinant protein (2).

IHC

Figure 2 Mouse Anti-ERBB3 Recombinant Antibody (ZG-0313J) in IHC

Figure 2 Mouse Anti-ERBB3 Recombinant Antibody (ZG-0313J) in IHC

Immunohistochemistry analysis of paraffin-embedded human cerebra (left) and breast carcinoma tissue (right), showing cytoplasmic and membrane location with DAB staining using ErbB-3 Monoclonal Antibody

Subcellular Location and Protein Expression

Figure 1 IF staining of human cell line U-2 OS
(Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & actin filaments.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25331/if_selected.jpg

Figure 2 IHC staining of human testis
(Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts and Leydig cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/ihc_selected.jpg

Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/70524/162441_A_4_2_selected.jpg

Figure 4 IHC staining of human kidney
(Immunohistochemical staining of human kidney shows strong cytoplasmic and membranous positivity in renal tubular cells.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25331/67596_A_8_5_selected.jpg

Figure 5 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25331/659_B11_4_blue_red_green.jpg

Figure 6 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25331/658_B11_1_blue_red_green.jpg

Normal Tissue

Figure 7 Cerebral cortex
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Neuronal cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous nuclear
Neuropil
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/115200_B_7_5.jpg

Figure 8 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/25331/67596_A_9_3.jpg

Figure 9 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Hepatocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/114856_A_8_4.jpg

Figure 10 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/114856_A_9_5.jpg

Figure 11 Testis
(Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Leydig cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/114856_A_4_6.jpg

Figure 12 Skin
(Fibroblasts
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Keratinocytes
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Langerhans
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Melanocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/115200_B_8_1.jpg

Figure 13 Lymph node
(Non-germinal center cells
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/45396/114856_A_9_8.jpg

RNA Expression

Figure 14 RNA cell line category: Cell line enhanced (Hep G2, OE19, RT4, SK-BR-3, SK-MEL-30, T-47d, WM-115)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000065361-ERBB3

Datasheet

MSDS

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Specifications

Immunogen
Purified recombinant fragment of ErbB-3 (aa1175-1275) expressed in E.

Host Species
Mouse

Type
Mouse IgG

Specificity
Human ERBB3

Species Reactivity
Human

Applications
WB, IHC, ELISA

Product Property

Storage
Store at 4°C for short term. For long term storage, store at-20°C, avoiding freeze/thaw cycles.

Applications

Application Notes
The antibody was validated for Western Blot, Immunohistochemistry, Enzyme-linked Immunosorbent Assay.

Target

Alternative Names
HER3; FERLK; LCCS2; VSCN1; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3; receptor tyrosine-protein kinase erbB-3; human epidermal growth factor receptor 3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3

Gene ID
2065

UniProt ID
P21860

Related Resources

Related Diseases
Related Signaling Pathways

EGFR Tyrosine Kinase Inhibitor Resistance

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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CAT	Product Name	Application	Type
TAB-892	Anti-Human ERBB3/ErbB 3 Recombinant Antibody (Seribantumab)	IF, IP, Neut, FuncS, ELISA, FC, ICC	IgG2 - lambda
TAB-057CT-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-057CT-F(E))	Inhibion, ELISA	Humanized Fab
TAB-058CT-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-058CT-F(E))	WB, ELISA, Inhib	Humanized Fab
TAB-059CT-F(E)	Anti-Human HER3 Recombinant Antibody Fab Fragment (LMAb3)	WB, ELISA, Inhibition, FC	Humanized antibody
TAB-063CT-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-063CT-F(E))	ELISA, Inhib, FC	Humanized Fab

CAT	Product Name	Application	Type
PABL-086	Human Anti-ERBB3 Recombinant Antibody (clone KTN3379)	ELISA, WB, IF, FuncS	Human IgG
HPAB-0286-YC	Mouse Anti-ERBB3 Recombinant Antibody (clone 1153)	ELISA, FuncS, FC	Mouse IgG
HPAB-0287-YC	Mouse Anti-ERBB3 Recombinant Antibody (clone 920104)	ELISA, FuncS, FC	Mouse IgG
HPAB-0288-YC	Mouse Anti-ERBB3 Recombinant Antibody (clone 1126)	ELISA, FuncS, FC	Mouse IgG
HPAB-0289-YC	Mouse Anti-ERBB3 Recombinant Antibody (clone 12511)	ELISA, FuncS, FC	Mouse IgG

CAT	Product Name	Application	Type
PSBL-086	Human Anti-ERBB3 Recombinant Antibody (clone KTN3379); scFv Fragment	ELISA, WB, IF, FuncS	Human scFv
PSBL-127	Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBL-127)	ELISA, WB, FuncS	Human scFv
PSBL-128	Mouse Anti-ERBB3 Recombinant Antibody; scFv Fragment (PSBL-128)	WB, Block, FuncS	Mouse scFv
HPAB-0286-YC-S(P)	Mouse Anti-ERBB3 Recombinant Antibody (clone 1153); scFv Fragment	ELISA, FuncS, FC	Mouse scFv
HPAB-0287-YC-S(P)	Mouse Anti-ERBB3 Recombinant Antibody (clone 920104); scFv Fragment	ELISA, FuncS, FC	Mouse scFv

CAT	Product Name	Application	Type
TAB-0033CL	Human Anti-ERBB3 Recombinant Antibody (TAB-0033CL)	ELISA, FuncS, Inhib, FC	Human IgG
TAB-0034CL	Human Anti-ERBB3 Recombinant Antibody (TAB-0034CL)	ELISA, FuncS, Inhib, FC	Human IgG
TAB-0035CL	Human Anti-ERBB3 Recombinant Antibody (TAB-0035CL)	ELISA, FuncS, Inhib, FC	Human IgG
TAB-0036CL	Human Anti-ERBB3 Recombinant Antibody (TAB-0036CL)	ELISA, FuncS, Inhib, FC	Human IgG
TAB-0037CL	Human Anti-ERBB3 Recombinant Antibody (TAB-0037CL)	ELISA, FuncS, Inhib, FC	Human IgG

CAT	Product Name	Application	Type
TAB-0552CL-F(E)	Mouse Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-0552CL-F(E))	ELISA, Inhib	Mouse Fab
TAB-0553CL-F(E)	Mouse Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-0553CL-F(E))	ELISA, Inhib	Mouse Fab
TAB-060CT-F(E)	Rabbit Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-060CT-F(E))	Inhib, ELISA	Rabbit Fab
TAB-064CT-F(E)	Mouse Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-064CT-F(E))	ELISA, FC	Mouse Fab
TAB-067CT-F(E)	Anti-Human HER3 Recombinant Antibody Fab Fragment (5101)	ELISA, Inhibition, FC

CAT	Product Name	Application	Type
TAB-061CT	Human Anti-ERBB3 Recombinant Antibody (TAB-061CT)	Inhib, ELISA	Chimeric (Rabbit/Human) antibody
TAB-061CT-S(P)	Human Anti-ERBB3 Recombinant Antibody; scFv Fragment (TAB-061CT-S(P))	Inhib, ELISA	Human scFv
TAB-061CT-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (TAB-061CT-F(E))	Inhib, ELISA	Chimeric (Rabbit/Human) Fab

CAT	Product Name	Application	Type
NEUT-738CQ	Mouse Anti-ERBB3 Recombinant Antibody (clone CBL932)	Neut, IP	Mouse IgG1
NEUT-739CQ	Mouse Anti-ERBB3 Recombinant Antibody (clone CBL483)	FC, CyTOF®, ELISA, Neut	Mouse IgG1
NEUT-740CQ	Human Anti-ERBB3 Recombinant Antibody (clone CBL1019)	Neut	Human IgG1, κ
NEUT-741CQ	Human Anti-ERBB3 Recombinant Antibody (clone CBL1020)	Neut	Human IgG1, κ
NEUT-742CQ	Mouse Anti-ERBB3 Recombinant Antibody (NEUT-742CQ)	Neut	Mouse IgG1

CAT	Product Name	Application	Type
HPAB-0081-FY-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0081-FY-F(E))	Inhib	Humanized Fab
HPAB-0120-FY-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0120-FY-F(E))	ELISA, WB	Humanized Fab
HPAB-0128-FY-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0128-FY-F(E))	ELISA	Human Fab, κ
HPAB-0181-FY-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0181-FY-F(E))	FC	Human Fab
HPAB-0182-FY-F(E)	Human Anti-ERBB3 Recombinant Antibody; Fab Fragment (HPAB-0182-FY-F(E))	FC	Human Fab

CAT	Product Name	Application	Type
AFC-TAB-H21	Afuco™ Anti-ERBB3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H21)	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody
AFC-TAB-422CQ	Afuco™ Anti-ERBB3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-422CQ)	ELISA, IHC, FC, IP, IF, BL	ADCC enhanced antibody
AFC-TAB-189	Afuco™ Anti-ERBB3 Recombinant Antibody (AFC-TAB-189), ADCC Enhanced	IP, IF, FuncS, FC, Neut, ELISA	Human IgG1, κ
AFC-TAB-H22	Afuco™ Anti-ERBB3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H22)	ELISA, IP, FC, FuncS, Neut, IF	ADCC enhanced antibody
AFC-TAB-892	Afuco™ Anti-ERBB3 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-892)	IF, IP, Neut, FuncS, ELISA, FC	ADCC enhanced antibody

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VS-0424-XY92	AbPlus™ Anti-ERBB3 Magnetic Beads (Duligotuzumab)	IP, Protein Purification
VS-0724-YC1400	AbPlus™ Anti-ERBB3 Magnetic Beads (VS-0724-YC1400)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0125-FY22	Human Anti-ERBB3 (clone H3) scFv-Fc Chimera	ELISA, Inhib	Human IgG1, scFv-Fc
VS-0125-FY23	Human Anti-ERBB3 (clone PM6) scFv-Fc Chimera	WB, ELISA, IHC, FuncS, BI	Human IgG1, scFv-Fc