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CD22 & saporin

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CD22 (CD22 Molecule) is a Protein Coding gene. Diseases associated with CD22 include Refractory Hematologic Cancer and Refractory Hairy Cell Leukemia. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and Innate Immune System. Gene Ontology (GO) annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC1.

Saporin is a so-called ribosome inactivating protein (RIP), due to its N-glycosidase activity, from the seeds of Saponaria officinalis (common name: soapwort).Saporin depurinate the ribosomal RNA in a specific position; rendering the large subunit of ribosomes unable to bind the elongation factors. The consequent arrest of protein synthesis is responsible for the cytotoxicity.

Anti-CD22 & saporin Recombinant Antibody Products

Anti-Human CD22 Recombinant Antibody (Epratuzumab) (TAB-176)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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Anti-Human CD22 Recombinant Antibody (Moxetumomab Pasudotox) (TAB-183-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fv - disulfide stabilized
- Application: FuncS, IF, Neut, ELISA, FC, IP, ICC
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Humanized Anti-CD22 Recombinant Antibody (clone Inotuzumab) (TAB-198)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG4, κ
- Application: ELISA, FC, IP, FuncS, IF, Neut, ICC
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Mouse Anti-Human CD22 Recombinant Antibody (TAB-003LC)
- Application: FC
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Mouse Anti-CD22 Recombinant Antibody (TAB-005LC) (TAB-005LC)
- Species Reactivity: Human
- Type: Mouse IgG2b
- Application: FC, Cyt, Block, Apop, ROS assay, FuncS
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Anti-Human CD22 Recombinant Antibody (4G6) (TAB-1719CL)
- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody (21F6) (TAB-1720CL)
- Derivation: Human
- Type: Fully human antibody
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody (CD22.1) (TAB-1721CL)
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Anti-Human CD22 Recombinant Antibody (CD22.2) (TAB-1722CL)
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Anti-Human CD22 Recombinant Antibody (RFB4) (TAB-1728CL)
- Application: IF, FC
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Anti-Human CD22 Recombinant Antibody (16F7) (TAB-1717CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Anti-Human CD22 Recombinant Antibody (23C6) (TAB-1718CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Anti-Human CD22 Recombinant Antibody scFv Fragment (12C5) (TAB-1715CL-S(P))
- Derivation: Human
- Type: Fully human antibody
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Human Anti-CD22 Recombinant Antibody (TAB-1729CL) (TAB-1729CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: IF, FC
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Anti-Human CD22 Recombinant Antibody scFv Fragment (hLL2) (TAB-0196CL-S(P))
- Application: ELISA, In vivo
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Anti-Human CD22 Recombinant Antibody scFv Fragment (hLL2-Cys) (TAB-0197CL-S(P))
- Application: ELISA, In vivo
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Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1724CL-S(P)) (TAB-1724CL-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib
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Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1725CL-S(P)) (TAB-1725CL-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: Block, Cyt, ELISA, FuncS
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Anti-Human CD22 Recombinant Antibody (12C5) (TAB-1715CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Anti-Human CD22 Recombinant Antibody (19A3) (TAB-1716CL)
- Derivation: Human
- Type: Fully human antibody
- Application: Cyt, FuncS
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Human Anti-CD22 Recombinant Antibody (TAB-1724CL) (TAB-1724CL)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) IgG1, κ
- Application: Inhib
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Human Anti-CD22 Recombinant Antibody (TAB-1725CL) (TAB-1725CL)
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized IgG
- Application: Block, Cyt, ELISA, FuncS
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Anti-Human CD22 Recombinant Antibody (hLL2-Cys) (TAB-0197CL)
- Application: ELISA, In vivo
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Anti-Human CD22 Recombinant Antibody Fab Fragment (12C5) (TAB-1715CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody Fab Fragment (19A3) (TAB-1716CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody Fab Fragment (16F7) (TAB-1717CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody scFv Fragment (CD22.2) (TAB-1722CL-S(P))
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Human Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1729CL-S(P)) (TAB-1729CL-S(P))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized scFv
- Application: IF, FC
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Anti-Human CD22 Recombinant Antibody scFv Fragment (19A3) (TAB-1716CL-S(P))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody scFv Fragment (16F7) (TAB-1717CL-S(P))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody scFv Fragment (23C6) (TAB-1718CL-S(P))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody scFv Fragment (4G6) (TAB-1719CL-S(P))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody scFv Fragment (21F6) (TAB-1720CL-S(P))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody scFv Fragment (CD22.1) (TAB-1721CL-S(P))
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-001LC-S(P)) (TAB-001LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody scFv Fragment (VM1000) (TAB-002LC-S(P))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, SPR
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Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1724CL-F(E)) (TAB-1724CL-F(E))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric (mouse/human) Fab
- Application: Inhib
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Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1725CL-F(E)) (TAB-1725CL-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: Block, Cyt, ELISA, FuncS
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Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2) (TAB-0196CL-F(E))
- Application: ELISA, In vivo
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Anti-Human CD22 Recombinant Antibody Fab Fragment (hLL2-Cys) (TAB-0197CL-F(E))
- Application: ELISA, In vivo
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Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1729CL-F(E)) (TAB-1729CL-F(E))
- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized Fab
- Application: IF, FC
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Human Anti-CD22 Recombinant Antibody (TAB-001LC) (TAB-001LC)
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody (VM1000) (TAB-002LC)
- Derivation: Humanized
- Type: Humanized antibody
- Application: FC, ELISA, SPR, FuncS
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Anti-Human CD22 Recombinant Antibody Fab Fragment (23C6) (TAB-1718CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody Fab Fragment (4G6) (TAB-1719CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody Fab Fragment (21F6) (TAB-1720CL-F(E))
- Derivation: Human
- Type: Fully human antibody
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Anti-Human CD22 Recombinant Antibody Fab Fragment (CD22.1) (TAB-1721CL-F(E))
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Anti-Human CD22 Recombinant Antibody Fab Fragment (CD22.2) (TAB-1722CL-F(E))
- Type: Human antibody
- Application: ELISA, FC, FuncS
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Human Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-001LC-F(E)) (TAB-001LC-F(E))
- Derivation: Chimeric (mouse/human)
- Species Reactivity: Human
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
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Anti-Human CD22 Recombinant Antibody Fab Fragment (VM1000) (TAB-002LC-F(E))
- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, SPR
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Humanized Anti-CD22 Recombinant Antibody (clone Pinatuzumab) (TAB-899)
- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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Anti-Human CD22 Recombinant Antibody (hLL2) (TAB-0196CL)
- Application: Inhib, Cyt, FC, WB
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Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-005LC-F(E)) (TAB-005LC-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: FC
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Anti-Human CD22 Recombinant Antibody Fab Fragment(Bectumomab) (TAB-047-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Fab' - G2a - kappa
- Application: ELISA, FC, IP, FuncS, IF, Neut, WB
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Mouse Anti-Human CD22 Recombinant Antibody Fab Fragment (TAB-003LC-F(E))
- Application: FC
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Anti-Human CD22 Recombinant Antibody Fab Fragment (TAB-004LC-F(E))
- Application: FC
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Anti-Human CD22 Recombinant Antibody (TAB-004LC)
- Application: FC
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Anti-Human CD22 Recombinant Antibody scFv Fragment (TAB-004LC-S(P))
- Application: FC
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Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-005LC-S(P)) (TAB-005LC-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: FC
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Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1723CL-F(E)) (TAB-1723CL-F(E))
- Species Reactivity: Human
- Type: Mouse Fab
- Application: Inhib
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Mouse Anti-CD22 Recombinant Antibody; Fab Fragment (TAB-1714CL-F(E)) (TAB-1714CL-F(E))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, WB
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Anti-Human CD22 Recombinant Antibody Fab Fragment (RFB4) (TAB-1728CL-F(E))
- Application: IF, FC
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Mouse Anti-Human CD22 Recombinant Antibody scFv Fragment (TAB-003LC-S(P))
- Application: FC
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Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1723CL-S(P)) (TAB-1723CL-S(P))
- Species Reactivity: Human
- Type: Mouse scFv
- Application: Inhib
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Mouse Anti-CD22 Recombinant Antibody (TAB-1714CL) (TAB-1714CL)
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, WB
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Anti-Human CD22 Recombinant Antibody scFv Fragment (RFB4) (TAB-1728CL-S(P))
- Application: IF, FC
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Mouse Anti-CD22 Recombinant Antibody; scFv Fragment (TAB-1714CL-S(P)) (TAB-1714CL-S(P))
- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, WB
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Hi-Affi™ Rabbit Anti-CD22 Recombinant Antibody (clone DS545AB) (MOR-0545)
- Derivation: Phage display library screening
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: IP, WB
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