Human Anti-CD46 Recombinant Antibody (clone K53); Fab Fragment

Name: Human Anti-CD46 Recombinant Antibody (clone K53); Fab Fragment
SKU: HPAB-2050-FY-F(E)
Rating: 5 (1 reviews)

CAT#: HPAB-2050-FY-F(E)

This product is a recombinant human antibody Fab Fragment that recognizes CD46. The monoclonal human antibody Fab Fragment K53 reacts with the epitope of CD46.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line MCF7

Immunofluorescent staining of human cell line MCF7 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67463/1592_H11_2_selected.jpg

Normal Tissue Figure 2 Thyroid gland

Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_B_2_5.jpg

Normal Tissue Figure 3 Colon

Endocrine cells
Staining: High
Intensity: Strong
Enterocytes
Staining: High
Intensity: Strong
Quantity:>75%
Enterocytes - Microvilli
Staining: High
Intensity: Strong
Goblet cells
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_9_3.jpg

Normal Tissue Figure 4 Kidney

Collecting ducts
Staining: High
Intensity: Strong
Quantity:>75%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/55098/120585_A_8_5.jpg

RNA Expression Figure 5 RNA cell line category: Cell line enhanced (A-431, CACO-2, CAPAN-2, OE19, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000119888-EPCAM

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Specifications

Host Species
Human

Type
Human Fab, κ

Specificity
Human CD46

Species Reactivity
Human

Applications
Flow Cytometry

Product Property

Purity
>95% as determined by SDS-PAGE analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Applications

Application Notes
The CD46 antibody has been reported in applications of Flow Cytometry.

Target

Alternative Names
CD46, AHUS2, MCP, MIC10, TLX, TRA2.10, CD46 molecule

Gene ID
4179

UniProt ID
P15529

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-2050-FY-F(E).pdf

MSDS

MSDS - HPAB-2050-FY-F(E).pdf

COA

Certificate of Analysis Lookup

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