Recombinant Rabbit Anti-CD40 Capture Antibody (clone R16-7B-9)

Name: Recombinant Rabbit Anti-CD40 Capture Antibody (clone R16-7B-9)
SKU: VS3-WK1816
Rating: 5 (1 reviews)

CAT#: VS3-WK1816

This antibody is a rabbit recombinant antibody against human CD40. It was developed by immunization of rabbit with recombinant human CD40 protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. The sandwich ELISA was established using matched antibody pair R16-7B-9 and R67-1K-7. The clone R16-7B-9 can be used as a capture antibody in ELISA analysis to identify human CD40.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/72868/156401_A_8_8.jpg

Normal Tissue Figure 2 Tonsil

Germinal center cells
Staining: High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/31567/156626_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (CAPAN-2, Daudi, EFO-21)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000101017-CD40

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Specifications

Immunogen
Recombinant human CD40 protein

Host Species
Rabbit

Type
Rabbit IgG

Specificity
Human CD40

Species Reactivity
Human

Clone
R16-7B-9

Applications
ELISA

Conjugate
Unconjugated

Product Property

Clonality
Monoclonal

Purification
Protein A affinity purified

Purity
>95% as determined by SDS-PAGE

Aggregation
< 5%

Format
Liquid

Concentration
Please refer to the vial label for the specific concentration.

Buffer
0.01M PBS, pH 7.2

Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping
Ice packs

Target

Alternative Names
CD40 Molecule; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily, Member 5

Gene ID
958

UniProt ID
P25942

Long Name
CD40 Molecule

Cellular Localization
Cell membrane, Membrane, Secreted

Protein Refseq
NP_001241.1; NP_001289682.1; NP_001309351.1

Function
Receptor for TNFSF5/CD40LG.
Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion (By similarity).

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Related Diseases

Asthma

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Autoimmune Thyroid Disease

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS3-WK1816.pdf

MSDS

MSDS - VS3-WK1816.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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Detection antibody

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