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    FcγRII & CD79B

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    Anti-FcγRII & CD79B Products

    • Anti-CD79b (clone ch2F2)-SMCC-DM1 ADC (ADC-202CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79b (clone hu2F2.D7)-SMCC-DM1 ADC (ADC-203CL)
      • Target: CD79b
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79 (bSN8)-mcc-DM1 ADC (ADC-089LCT)
      • Target: CD79b
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
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    • Anti-CD79b-vc-MMAE ADC (ADC-034LZY)
      • Target: CD79b
      • Linker: VC(Valine-citrulline)
      • Drug: MMAE (monomethyl auristatin E)
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    • Anti-CD79b-MCC-DM1 ADC (ADC-084LZY)
      • Target: CD79b
      • Linker: MCC (4-(Nmaleimidomethyl)cyclohexane-1 carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b-mc-MMAF ADC (ADC-085LZY)
      • Target: CD79b
      • Linker: mc(maleimidocaproyl)
      • Drug: MMAF(monomethyl auristatin F)
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    • Anti-CD79b (clone SN8)-SPP-DM1 ADC (ADC-201LZY)
      • Target: CD79b
      • Linker: SPP(N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-CD79b (clone SN8)-MCC-DM1 ADC (ADC-202LZY)
      • Target: CD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    • Anti-cyCD79b (clone 10D10)-MCC-DM1 ADC (ADC-216LZY)
      • Target: cyCD79b
      • Linker: MCC(Maleimidomethyl cyclohexane-1-carboxylate))
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
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    For Research Use Only. Not For Clinical Use.


    Background

    The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
    The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-beta protein of the B-cell antigen component.
    FcγRII & CD79B
    Related Signaling Pathways
    BCR Signaling Pathway BCR Signaling Pathway
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