Afuco™ Anti-EGFR ADCC Recombinant Antibody (Imgatuzumab), ADCC Enhanced (CAT#: AFC-TAB-753)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from rat) antibody expressed in CHO binding to human EGFR. Imgatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator.

Host: Human

Isotype: ADCC enhanced antibody

Applications: Neut, ELISA, IF, IP, FuncS, FC


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA

Subcellular Location and Protein Expression

Normal Tissue

RNA Expression


Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Humanized (from rat)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Imgatuzumab
  • Applications
  • Neut, ELISA, IF, IP, FuncS, FC
  • Conjugate
  • Unconjugated
  • Generic Name
  • Imgatuzumab
  • Related Disease
  • Solid tumors

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Imgatuzumab; 959963-46-3; RG7160; GA201; RO5083945; ICR62; EGFR; epidermal growth factor receptor; epidermal growth factor receptor (avian erythroblastic leukemia viral (v erb b) oncogene homolog), ERBB; ERBB1;

Related Resources

  • Biosimilar Overview
  • Related Diseases
  • Related Signaling Pathways
Please refer to Imgatuzumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Imgatuzumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "imgatuzumab"

Anti-EGFR Recombinant Antibody (Imgatuzumab)
Recombinant humanized (from rat) antibody expressed in CHO binding to human EGFR. Imgatuzumab is a humanized monoclonal antibody designed for the treatment of cancer. It acts as an immunomodulator.

See other products for "EGFR"

Human Antibody

CAT Product Name Application Type
TAB-020 Anti-Human EGFR Recombinant Antibody (Panitumumab) ELISA, IP, FC, FuncS, Neut, IF, ICC IgG2 - kappa
TAB-299MZ-F(E) Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-299MZ-F(E)) Internalization Assay Human Fab
PABX-053 Recombinant Human Anti-EGFR Antibody (DL11) WB, ELISA, FuncS IgG
PABX-052-S (P) Recombinant Human Anti-EGFR Antibody scFv Fragment (Nimotuzumab) WB, ELISA, FuncS scFv
PABX-053-S (P) Recombinant Human Anti-EGFR Antibody scFv Fragment (DL11) WB, ELISA, FuncS scFv

Humanized Antibody

CAT Product Name Application Type
TAB-165 Anti-Human EGFR Recombinant Antibody (Matuzumab) Neut, ELISA, IF, IP, FuncS, FC, ICC IgG1
TAB-753 Anti-EGFR Recombinant Antibody (Imgatuzumab) Neut, ELISA, IF, IP, FuncS, FC, WB IgG1 - kappa
TAB-274MZ Human Anti-EGFR Recombinant Antibody (TAB-274MZ) FC Humanized IgG
TAB-274MZ-S(P) Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-274MZ-S(P)) FC Humanized scFv
TAB-274MZ-F(E) Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-274MZ-F(E)) FC Humanized Fab

Single-domain Antibody

CAT Product Name Application Type
PNBL-016 Recombinant Anti-Human EGFR VHH Single Domain Antibody (7D12) WB, ELISA Llama VHH
PNBL-017 Recombinant Anti-Human EGFR VHH Single Domain Antibody (9G8) FuncS, ELISA, IF Llama VHH
PNBL-018 Recombinant Anti-Human EGFR VHH Single Domain Antibody (EgA1) FuncS, SPR Llama VHH
HPAB-AP881-YC Recombinant Llama Anti-EGFR Single Domain Antibody (VHH122) ELISA, FC, IP, FuncS Llama VHH
HPAB-AP882-YC Recombinant Llama Anti-EGFR Single Domain Antibody (VHH205) ELISA Llama VHH

Recombinant Antibody

CAT Product Name Application Type
PFBW-088 Mouse Anti-EGFR Recombinant Antibody (clone 7A7); Fab Fragment ELISA, WB Mouse Fab
MOB-0094MZ Recombinant Mouse Anti-EGFR Antibody (clone FGF-R2) ELISA, IHC-P, FC Mouse antibody
HPAB-0010-YC Mouse Anti-EGFR Recombinant Antibody (clone L211C) ELISA, FC Mouse IgG
HPAB-0011-YC Human Anti-EGFR Recombinant Antibody (clone Pep 1) FC Human IgG
HPAB-0012-YC Human Anti-EGFR Recombinant Antibody (clone Pep 2) FC Human IgG

Chimeric Antibody

CAT Product Name Application Type
TAB-0225CL-F(E) Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-0225CL-F(E)) Block, Inhib, FuncS, Apop, In vivo Chimeric (Mouse/Human) Fab
TAB-272MZ-S(P) Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-272MZ-S(P)) FuncS Mouse scFv
TAB-272MZ-F(E) Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-272MZ-F(E)) FuncS Chimeric (mouse/human) Fab
TAB-302MZ-F(E) Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-302MZ-F(E)) ELISA Chimeric (mouse/human) Fab
PABX-051 Recombinant Human Anti-EGFR Antibody (Matuzumab) WB, Neut, FuncS, FC, ELISA, IF, Inhib IgG

Mouse Antibody

CAT Product Name Application Type
TAB-326MZ-S(P) Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-326MZ-S(P)) FC Mouse scFv
TAB-304MZ-F(E) Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-304MZ-F(E)) ELISA Mouse Fab
TAB-305MZ-F(E) Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-305MZ-F(E)) ELISA Mouse Fab
TAB-306MZ-F(E) Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-306MZ-F(E)) ELISA Mouse Fab
TAB-326MZ-F(E) Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-326MZ-F(E)) FC Mouse Fab

Fc Glycosylation

CAT Product Name Application Type
Gly-055LC Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Chimeric antibody (mouse/human)
Gly-144LC Recombinant Anti-Human EGFR Antibody (Fc glycosylation) ELISA Humanized antibody

High-mannose Glycoform

CAT Product Name Application Type
Gly-055LC-1 Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated) ELISA Chimeric antibody (mouse/human)

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT Product Name Application Type
Gly-167LC Recombinant Anti-Human EGFR Antibody (Non-glycosylated) ELISA Human antibody

Chicken IgY Antibody

CAT Product Name Application Type
BRD-0183MZ Chicken Anti-EGFR Polyclonal IgY WB Chicken antibody
BRD-0668MZ Chicken Anti-EGFR Polyclonal IgY WB Chicken antibody

MHC Tetramer for Cancer

CAT Product Name Application Type
MHC-LC773 A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer FCM
MHC-LC4545 PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer FCM
MHC-YF409 A*02:01/Human EGF-R-479 (KLFGTSGQKT) MHC Pentamer FCM

Neutralizing Antibody

CAT Product Name Application Type
NEUT-722CQ Rabbit Anti-EGFR Recombinant Antibody (clone CBL1011) Neut Rabbit IgG
NEUT-723CQ Mouse Anti-EGFR Recombinant Antibody (clone CBL931) WB, IP, IHC, ICC, Neut Mouse IgG1
NEUT-724CQ Rabbit Anti-EGFR Recombinant Antibody (clone D1D4J) IF, FC, WB, IP, Neut Rabbit IgG

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-1101 Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone DS1101AB) IHC-P Rabbit IgG
MOR-4520 Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH28DS) IF, ICC, FC Rabbit IgG
MOR-4570 Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH82DS) ELISA Rabbit IgG
MOR-4571 Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH83DS) WB, IF, ICC, FC Rabbit IgG
MOR-4675 Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH189DS) WB, IF, ICC, FC Rabbit IgG

Fab Fragment Antibody

CAT Product Name Application Type
FAMAB-0094-YC-F(E) Human Anti-EGFR Recombinant Antibody (clone F4); Fab Fragment ELISA, WB, FC Human Fab
HPAB-0044-FY-F(E) Human Anti-EGFR Recombinant Antibody (clone TGM10-1); Fab Fragment FC Humanized Fab
HPAB-0089-FY-F(E) Human Anti-EGFR Recombinant Antibody (clone MIL27-3); Fab Fragment FC Humanized Fab
HPAB-0119-FY-F(E) Human Anti-EGFR Recombinant Antibody (clone huML66); Fab Fragment Inhib Humanized Fab
HPAB-0122-FY-F(E) Mouse Anti-EGFR Recombinant Antibody (clone L2-H3); Fab Fragment ELISA, WB Humanized Fab

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-165 Afuco™ Anti-EGFR ADCC Recombinant Antibody (Matuzumab), ADCC Enhanced Neut, ELISA, IF, IP, FuncS, FC ADCC enhanced antibody
AFC-TAB-464CQ Afuco™ Anti-EGFR ADCC Recombinant Antibody (Tomuzotuximab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-003 Afuco™ Anti-EGFR ADCC Recombinant Antibody (Cetuximab), ADCC Enhanced IF, IP, Neut, FuncS, ELISA, FC ADCC enhanced antibody
AFC-TAB-710 Afuco™ Anti-EGFR ADCC Recombinant Antibody (Nimotuzumab), ADCC Enhanced ELISA, IP, FC, FuncS, Neut, IF ADCC enhanced antibody
AFC-TAB-H35 Afuco™ Anti-EGFR ADCC Recombinant Antibody (Futuximab), ADCC Enhanced FuncS, IF, Neut, ELISA, FC, IP ADCC enhanced antibody

scFv Fragment Antibody

CAT Product Name Application Type
HPAB-S0018-YC-S(P) Human Anti-EGFR Recombinant Antibody (clone E2.5); scFv Fragment ELISA, Inhib, FuncS Human scFv
HPAB-S0019-YC-S(P) Human Anti-EGFR Recombinant Antibody (clone E2.11); scFv Fragment ELISA, Inhib Human scFv
HPAB-S0020-YC-S(P) Human Anti-EGFR Recombinant Antibody (clone E6.2); scFv Fragment ELISA, Inhib Human scFv
HPAB-S0021-YC-S(P) Human Anti-EGFR Recombinant Antibody (clone E6.3); scFv Fragment ELISA, Inhib Human scFv
HPAB-S0022-YC-S(P) Human Anti-EGFR Recombinant Antibody (clone E7.6.3); scFv Fragment ELISA, Inhib, FuncS Human scFv

Customer Reviews and Q&As

Submit a review or a question
There are currently no Customer reviews or questions for AFC-TAB-753. Click the button above to contact us or submit your feedback about this product.
View the frequently asked questions answered by Creative Biolabs Support.

For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

* Abbreviations
Send Inquiry
© 2023 Creative BioLabs. All Rights Reserved
  • 0
  • 0
Cart