Anti-EGFR Antibody-Cytokine Fusion Protein, IgG-IL2 (CAT#: ACFP-SH155)

This antibody-cytokine fusion protein was achieved by conjugating/fusing the Anti-EGFR IgG to IL2. It was expressed in CHO and purified with affinity chromatography. The immunocytokine retains the ability to bind the EGFR as well as the biological activity of IL2. This immunocytokine was designed for treating any type of solid or non-solid cancer or malignant lymphoma.

Specific Inquiry
  • Size:
  • Conjugation:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location and Protein Expression
Normal Tissue
RNA Expression

Specifications

  • Target
  • EGFR
  • Molecule Class
  • IgG1-IL2
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Clone
  • trastuzumab
  • Related Disease
  • Any type of solid or non-solid cancer or malignant lymphoma
  • Cytokine 1
  • IL2
  • Cytokines 1 Description
  • Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, which are expressed by lymphocytes.
  • Cytokine 1 Species
  • Human
  • Applications
  • This product can be used therapeutically to deliver biologically active ligands to a desired tissue.

Target

  • Alternative Names
  • EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

Related Resources

  • Related Diseases
  • Related Signaling Pathways

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "EGFR"

Select a product category from the dropdown menu below to view related products.
Please select product type
IgG Antibody Products Humanized Antibody Products Human Antibody Products Chimeric Antibody Products Mouse Antibody Products Fc Glycosylation Antibody Products High-mannose Glycoform Antibody Products Deglycosylated Antibody Products Chicken IgY Antibody Products MHC Tetramer Products for Cancer Neutralizing Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products ADCC Enhanced Antibody Products Fab Antibody Products Single Domain Antibody Products Antibody Magnetic Beads Cancer Stem Cell Biomarker Specific Antibody Products Non-Human Primate (NHP) Antibody Products ScFv-Fc Chimera Products Flow Cytometry (FC) related Products

Customer Reviews and Q&As

Submit a review or a question

There are currently no Customer reviews or questions for ACFP-SH155. Click the button above to contact us or submit your feedback about this product.

Popular products with customers


For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

  • 0
  • 0
Cart
    Go to compare

    Go to compare