Anti-Human EGFR Recombinant Antibody (EG-19-11)

Published Data
Gene Expression
Datasheet
MSDS
COA

ELISA

Figure 1 Binding affinity was compared with EG-L2-11 by ELISA using a thiocyanate elution method.

Figure 2 Specific binding capacity of EG 19-11 was assessed by flow cytometry (FACScan (Becton-Dickinson, USA)) using A431 cells.

Subcellular Location and Protein Expression

Figure 1 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane & cell junctions.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/144_E9_2_selected.jpg

Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/143_E9_1_blue_red_green.jpg

Normal Tissue

Figure 3 Colon
(Glandular cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_3.jpg

Figure 4 Liver
(Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_4.jpg

Figure 5 Kidney
(Bowman's capsule
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Collecting ducts
Staining:Medium
Intensity: Strong
Quantity: <25%
Distal tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Proximal tubules (cell body)
Staining:Medium
Intensity: Strong
Quantity: <25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_9_5.jpg

Figure 6 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Pachytene spermatocytes
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Round or early spermatids
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_6_6.jpg

Figure 7 Placenta
(Cytotrophoblasts
Staining:High
Intensity: Strong
Quantity:>75%
Decidual cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Hofbauer cells
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - cell body
Staining:High
Intensity: Strong
Quantity:>75%
Syncytiotrophoblasts - microvilli
Staining:High
Intensity: Strong)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_1_7.jpg

Figure 8 Lymph node
(Non-germinal center cells
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18530/41191_A_7_8.jpg

RNA Expression

Figure 9 RNA cell line category: Cell line enriched (A-431)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000146648-EGFR

Datasheet

MSDS

Certificate of Analysis Lookup
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Lot Number

Specifications

Host Species
Human

Derivation
Library

Type
Human antibody

Specificity
Human

Clone
EG-19-11

Applications
ELISA, FC

Related Disease
Rectal cancer

Applications

Application Notes
This antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Flow Cytotoxicityometry.

Target

Alternative Names
EGFR; epidermal growth factor receptor; ERBB; HER1; mENA; ERBB1; PIG61; NISBD2; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; erb-b2 receptor tyrosine kinase 1; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog

Gene ID
1956

UniProt ID
P00533

Related Resources

Product Notes

Downloads

See other products for "Clone EG-19-11"

See other products for "EGFR"

Single-domain Antibody

CAT	Product Name	Application	Type
NABG-056	Recombinant Anti-Mouse Egfr VHH Single Domain Antibody	ELISA, IHC, FC, FuncS	Llama VHH
PNBL-016	Recombinant Anti-Human EGFR VHH Single Domain Antibody (7D12)	WB, ELISA	Llama VHH
PNBL-017	Recombinant Anti-Human EGFR VHH Single Domain Antibody (9G8)	FuncS, ELISA, IF	Llama VHH
PNBL-018	Recombinant Anti-Human EGFR VHH Single Domain Antibody (EgA1)	FuncS, SPR	Llama VHH
TAB-015MZ-VHH	Anti-Human EGFR Recombinant Antibody (PMP7A5)	sELISA	Single domain antibody

Chimeric Antibody

CAT	Product Name	Application	Type
TAB-H35	Anti-Human EGFR Recombinant Antibody (Futuximab)	IF, WB, Inhib	IgG1 - kappa
TAB-272MZ-S(P)	Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-272MZ-S(P))	FuncS	Mouse scFv
TAB-302MZ-S(P)	Mouse Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-302MZ-S(P))	ELISA	Mouse scFv
TAB-302MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-302MZ-F(E))	ELISA	Chimeric (mouse/human) Fab
TAB-308MZ-F(E)	Human Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-308MZ-F(E))	ELISA, FC	Chimeric antibody (mouse/human)

Human Antibody

CAT	Product Name	Application	Type
TAB-020	Anti-Human EGFR Recombinant Antibody (Panitumumab)	ELISA, IP, FC, FuncS, Neut, IF, ICC	IgG2 - kappa
TAB-299MZ-S(P)	Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-299MZ-S(P))	Internalization Assay	Human scFv
TAB-321MZ-S(P)	Anti-Human EGFR Recombinant Antibody scFv Fragment (DX 1-4)	SPR	Human antibody
PABX-053	Recombinant Human Anti-EGFR Antibody (DL11)	WB, ELISA, FuncS	IgG
PABX-053-F (E)	Recombinant Human Anti-EGFR Antibody Fab Fragment (DL11)	WB, ELISA, FuncS	Fab

Humanized Antibody

CAT	Product Name	Application	Type
TAB-753	Anti-EGFR Recombinant Antibody (Imgatuzumab)	Neut, ELISA, IF, IP, FuncS, FC, WB	IgG1 - kappa
TAB-274MZ	Human Anti-EGFR Recombinant Antibody (TAB-274MZ)	FC	Humanized IgG
TAB-300MZ	Human Anti-EGFR Recombinant Antibody (TAB-300MZ)	ELISA	Humanized IgG
TAB-274MZ-S(P)	Human Anti-EGFR Recombinant Antibody; scFv Fragment (TAB-274MZ-S(P))	FC	Humanized scFv
TAB-297MZ-S(P)	Anti-Human EGFR Recombinant Antibody scFv Fragment (H225)	ELISA, WB	Humanized antibody

Recombinant Antibody

CAT	Product Name	Application	Type
PABZ-039	Mouse Anti-EGFR Recombinant Antibody (clone mAb528)	FC	Mouse IgG
PABW-039	Human Anti-EGFR Recombinant Antibody (clone Cetuximab (IMC-C225))	FuncS	Chimeric (mouse/human) IgG
PABC-040	Human Anti-EGFR Recombinant Antibody (clone MR1)	Block	Human IgG
PABW-171	Mouse Anti-EGFR Recombinant Antibody (PABW-171)	WB	Mouse IgG
MOB-0094MZ	Recombinant Mouse Anti-EGFR Antibody (clone FGF-R2)	ELISA, IHC-P, FC	Mouse antibody

Fab Fragment Antibody

CAT	Product Name	Application	Type
PFBZ-039	Mouse Anti-EGFR Recombinant Antibody (clone mAb528); Fab Fragment	FC	Mouse Fab
PFBW-039	Human Anti-EGFR Recombinant Antibody (clone Cetuximab (IMC-C225)); Fab Fragment	FuncS	Chimeric (mouse/human) Fab
PFBC-040	Human Anti-EGFR Recombinant Antibody (clone MR1); Fab Fragment	Block	Human Fab
HPAB-1443LY-F(E)	Human Anti-EGFR Recombinant Antibody (clone P1X); Fab Fragment	ELISA, WB	Human Fab
HPAB-1444LY-F(E)	Human Anti-EGFR Recombinant Antibody (clone P2X); Fab Fragment	ELISA, WB	Human Fab

Mouse Antibody

CAT	Product Name	Application	Type
TAB-310MZ-F(E)	Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-310MZ-F(E))	ELISA	Mouse Fab
TAB-311MZ-F(E)	Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-311MZ-F(E))	ELISA	Mouse Fab
TAB-312MZ-F(E)	Mouse Anti-EGFR Recombinant Antibody; Fab Fragment (TAB-312MZ-F(E))	ELISA	Mouse Fab
TAB-316MZ-F(E)	Anti-Human EGFR Recombinant Antibody Fab Fragment (07D06)	WB, MTT assay
TAB-317MZ-F(E)	Anti-Human EGFR Recombinant Antibody Fab Fragment (12D03)	WB, MTT assay

Fc Glycosylation

CAT	Product Name	Application	Type
Gly-055LC	Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated)	ELISA	Chimeric antibody (mouse/human)
Gly-144LC	Recombinant Anti-Human EGFR Antibody (Fc glycosylation)	ELISA	Humanized antibody

High-mannose Glycoform

CAT	Product Name	Application	Type
Gly-055LC-1	Recombinant Anti-Human EGFR Antibody (Fc glycosylation/High-mannose glycosylated)	ELISA	Chimeric antibody (mouse/human)

Deglycosylated Antibody (Non-glycosylated IgGs)

CAT	Product Name	Application	Type
Gly-167LC	Recombinant Anti-Human EGFR Antibody (Non-glycosylated)	ELISA	Human antibody

Chicken IgY Antibody

CAT	Product Name	Application	Type
BRD-0183MZ	Chicken Anti-EGFR Polyclonal IgY	WB	Chicken antibody
BRD-0668MZ	Chicken Anti-EGFR Polyclonal IgY	WB	Chicken antibody

MHC Tetramer for Cancer

CAT	Product Name	Application	Type
MHC-LC773	A*0201/Human EGFR (YLNTVQPTCV) MHC Tetramer	FCM
MHC-LC4545	PE-DQB1*03:02/Human EGFR (SRALEEKKGNYVVTHG) MHC Tetramer	FCM
MHC-YF409	A*02:01/Human EGF-R-479 (KLFGTSGQKT) MHC Pentamer	FCM

Neutralizing Antibody

CAT	Product Name	Application	Type
NEUT-722CQ	Rabbit Anti-EGFR Recombinant Antibody (clone CBL1011)	Neut	Rabbit IgG
NEUT-723CQ	Mouse Anti-EGFR Recombinant Antibody (clone CBL931)	WB, IP, IHC, ICC, Neut	Mouse IgG1
NEUT-724CQ	Rabbit Anti-EGFR Recombinant Antibody (clone D1D4J)	IF, FC, WB, IP, Neut	Rabbit IgG

Rabbit Monoclonal Antibody

CAT	Product Name	Application	Type
MOR-1101	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone DS1101AB)	IHC-P	Rabbit IgG
MOR-4570	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH82DS)	ELISA	Rabbit IgG
MOR-4571	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH83DS)	WB, IF, ICC, FC	Rabbit IgG
MOR-4675	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH189DS)	WB, IF, ICC, FC	Rabbit IgG
MOR-4676	Hi-Affi™ Rabbit Anti-EGFR Recombinant Antibody (clone TH190DS)	WB, IF, ICC, FC	Rabbit IgG

ADCC Enhanced Antibody

CAT	Product Name	Application	Type
AFC-TAB-710	Afuco™ Anti-EGFR ADCC Recombinant Antibody (Nimotuzumab), ADCC Enhanced	ELISA, IP, FC, FuncS, Neut, IF	ADCC enhanced antibody
AFC-TAB-753	Afuco™ Anti-EGFR ADCC Recombinant Antibody (Imgatuzumab), ADCC Enhanced	Neut, ELISA, IF, IP, FuncS, FC	ADCC enhanced antibody
AFC-TAB-H35	Afuco™ Anti-EGFR ADCC Recombinant Antibody (Futuximab), ADCC Enhanced	FuncS, IF, Neut, ELISA, FC, IP	ADCC enhanced antibody
AFC-TAB-H49	Afuco™ Anti-EGFR ADCC Recombinant Antibody (Modotuximab), ADCC Enhanced	FuncS, IF, Neut, ELISA, FC, IP	ADCC enhanced antibody
AFC-TAB-020	Afuco™ Anti-EGFR ADCC Recombinant Antibody (Panitumumab), ADCC Enhanced	ELISA, IP, FC, FuncS, Neut, IF	ADCC enhanced antibody

scFv Fragment Antibody

CAT	Product Name	Application	Type
HPAB-0423-FY-S(P)	Human Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-0423-FY-S(P))	Agonist	Human scFv
HPAB-0424-FY-S(P)	Human Anti-EGFR Recombinant Antibody; scFv Fragment (HPAB-0424-FY-S(P))	IF	Human scFv
HPAB-1519-FY-F(E)	Human Anti-EGFR Recombinant Antibody (clone 15H8); scFv Fragment	ELISA	Human scFv
HPAB-AP637-YC-S(P)	Human Anti-EGFR Recombinant Antibody (clone EGL2); scFv Fragment	ELISA, FC, IF, Inhib	Human scFv
HPAB-S0023-YC-S(P)	Mouse Anti-EGFR Recombinant Antibody (clone 14E1); scFv Fragment	IB, FuncS	Mouse scFv

Customer Reviews and Q&As

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3D IHC3D Immunohistochemistry

ActivActivation

AgonistAgonist

ApopApoptosis

BABioassay

BIBioimaging

BlockBlocking

Cell ScreeningCell Screening

SeparationCell Separation

ChIPChromatin Immunoprecipitation

CMCDComplement Mediated Cell Depletion

CostimCostimulation